Oligonucleotides are short fragments of nucleic acids that are widely used in various areas of DNA diagnostics (medical diagnostics, forensic analysis, veterinary medicine, food quality control, etc.). Recently, oligonucleotides have been widely used in medicines against various genetic and other diseases. The GenTerra company produces DNA- and RNA- oligonucleotides on a scale of several milligrams to grams, including modified oligonucleotides, fluorescently-labeled oligonucleotides and probes for real-time PCR.