Blood serum is an extremely complex mixture of many small and large molecules. Of great importance for the quality of serum is the process of blood separation and pre - filtration purification of serum. For sterilization of blood serum of cattle the installation of sterilizing filtration is used. Blood serum of cattle is Packed in sterile glass containers (10 ml, 50 ml, 100 ml, 200 ml and 400 ml), sealed with sterile rubber stoppers and aluminum caps, labeled. Each batch is assigned a series number, which is displayed in the passport. Blood serum of cattle passes all necessary stages of check and, only after that, serum is delivered to clients. Blood serum of cattle is stored at a temperature of 4 + 20C for 1 year or frozen at-18oC for 2 years. The quality of the obtained blood serum of cattle makes it possible to use it not only as part of microbiological nutrient media, but also in the preparation of nutrient media for mammalian cell cultures.